Service-Oriented Architectures (SOA) are built as compositions of inter-organizational services. These services are deployed and published by providers who are responsible for provisioning the services with sufficient resources. However, even though services are implemented by technologies providing a wide range of adaptation related features, such as configurable component models and communication infrastructures, state-of-the-art approaches to adaptive SOA systems do not provide principled solutions to exploit application layer adaptation mechanisms. Our technology-agnostic adaptation middleware has been desig\-ned for integrating and exploiting technology-specific adaptation technologies and mechanisms. In this paper, we describe how this middleware can support a cross-layer adaptation of SOA systems. In particular, we focus on the server-side perspective of SOA, and we show that our middleware is able to exploit both service interface and application layers technologies for supporting a coordinated adaptation of both layers.